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KMID : 1134820210500121275
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Journal of the Korean Society of Food Science and Nutrition
2021 Volume.50 No. 12 p.1275 ~ p.1281
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Antioxidant Activity of Subcritical Water Extracts from Porphyra dentata and Their Effect on Blood Alcohol Levels in Acute Alcohol-Fed Rats
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Lee Hae-In
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Abstract
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This study investigated the antioxidant activity and alcohol-degrading effects of subcritical water extracts from Porphyra dentata (PD-SW) and compared them with hot-water extracts from Porphyra dentata (PD-W). Total polyphenol and flavonoid content, which are the major components responsible for the antioxidant activities of the PD-SW, were higher those in the PD-W. PD-SW also revealed higher antioxidant effects compared to the PD-W, which resulted in the down-regulation of the 2,2-diphenyl-1-picrylhydrazyl, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activities and ferric reducing antioxidant power values. The PD-SW showed a significant increase in hepatic alcohol dehydrogenase and aldehyde dehydrogenase activity when compared to the alcohol control, resulting in decreased plasma alcohol and acetaldehyde concentrations in acute alcohol-induced rats. Overall, PD-SW showed antioxidant activity and was effective in degrading alcohol in acute alcohol-fed rats. These results provide valuable information for applications of natural functional material.
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KEYWORD
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Porphyra dentata, laver, subcritical water extract, alcohol metabolic enzyme, antioxidant
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